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Crystallization chaperone strategies for membrane proteins

From G protein-coupled receptors to ion channels, membrane proteins represent over half of known drug targets. Yet, structure-based drug discovery is hampered by the dearth of available three-dimensional models for this large category of proteins. Other than efforts to improve membrane protein expre...

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Bibliografische gegevens
Gepubliceerd in:Methods
Hoofdauteurs: Lieberman, Raquel L., Culver, Jeffrey A., Entzminger, Kevin C., Pai, Jennifer C., Maynard, Jennifer A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186007/
https://ncbi.nlm.nih.gov/pubmed/21854852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2011.08.004
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