Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter

The MED1 subunit of the Mediator transcriptional coregulator complex is a nuclear receptor-specific coactivator. A negative feedback mechanism of thyroid-stimulating hormone (TSH, or thyrotropin) expression in the thyrotroph in the presence of triiodothyronine (T3) is employed by liganded thyroid ho...

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Foilsithe in:Biochem Biophys Res Commun
Main Authors: Matsui, Keiji, Oda, Kasumi, Mizuta, Shumpei, Ishino, Ruri, Urahama, Norinaga, Hasegawa, Natsumi, Roeder, Robert G., Ito, Mitsuhiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388257/
https://ncbi.nlm.nih.gov/pubmed/24055033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.09.061
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