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Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter
The MED1 subunit of the Mediator transcriptional coregulator complex is a nuclear receptor-specific coactivator. A negative feedback mechanism of thyroid-stimulating hormone (TSH, or thyrotropin) expression in the thyrotroph in the presence of triiodothyronine (T3) is employed by liganded thyroid ho...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388257/ https://ncbi.nlm.nih.gov/pubmed/24055033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.09.061 |
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