CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function

The MED1 subunit of the Mediator transcriptional coregulator complex coactivates GATA1 and induces erythropoiesis. Here, we show the dual mechanism of GATA1- and MED1-mediated transcription. MED1 expression levels in K562 erythroleukemia cells paralleled the levels of GATA1-targeted gene transcripti...

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Bibliografiske detaljer
Udgivet i:Genes Cells
Main Authors: Mizuta, Shumpei, Minami, Tomoya, Fujita, Haruka, Kaminaga, Chihiro, Matsui, Keiji, Ishino, Ruri, Fujita, Azusa, Oda, Kasumi, Kawai, Asami, Hasegawa, Natsumi, Urahama, Norinaga, Roeder, Robert G., Ito, Mitsuhiro
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388278/
https://ncbi.nlm.nih.gov/pubmed/24245781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12104
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