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The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220
The Mediator complex forms the bridge between transcriptional activators and RNA polymerase II. Mediator subunit Med1/TRAP220 is a key component of Mediator originally found to associate with nuclear hormone receptors. Med1 deficiency causes lethality at embryonic day 11.5 because of defects in hear...
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Auteurs principaux: | , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2006
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693692/ https://ncbi.nlm.nih.gov/pubmed/17132730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604494103 |
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