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MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation
We isolated MED25, which associates with retinoic acid (RA)-bound retinoic acid receptor (RAR) through the C-terminal nuclear hormone receptor (NR) box/LxxLL motif, and increases RAR/RXR-mediated transcription. When tethered to a promoter, MED25 showed intrinsic transcriptional activity in its PTOV...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1949011/ https://ncbi.nlm.nih.gov/pubmed/17641689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601797 |
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