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Retinoid signaling and Neurogenin2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP

Extracellular signals and cell-intrinsic transcription factors cooperatively instruct generation of diverse neurons. However, little is known about how neural progenitors integrate both cues and orchestrate chromatin changes for neuronal specification. Here, we report that extrinsic signal retinoic...

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Detalhes bibliográficos
Main Authors: Lee, Seunghee, Lee, Bora, Lee, Jae W., Lee, Soo-Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705669/
https://ncbi.nlm.nih.gov/pubmed/19524524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.04.025
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