The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

The Mediator complex forms the bridge between transcriptional activators and RNA polymerase II. Mediator subunit Med1/TRAP220 is a key component of Mediator originally found to associate with nuclear hormone receptors. Med1 deficiency causes lethality at embryonic day 11.5 because of defects in hear...

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Autors principals: Stumpf, Melanie, Waskow, Claudia, Krötschel, Marit, van Essen, Dominic, Rodriguez, Patrick, Zhang, Xiaoting, Guyot, Boris, Roeder, Robert G., Borggrefe, Tilman
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693692/
https://ncbi.nlm.nih.gov/pubmed/17132730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604494103
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