A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency

Nonviral gene and small interfering RNA (siRNA) delivery formulations are extensively used for biological and therapeutic research in cell culture experiments, but less so in in vivo and clinical research. Difficulties with formulating the nanoparticles for uniformity and stability at concentrations...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Tagalakis, Aristides D, Castellaro, Sara, Zhou, Haiyan, Bienemann, Alison, Munye, Mustafa M, McCarthy, David, White, Edward A, Hart, Stephen L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388080/
https://ncbi.nlm.nih.gov/pubmed/25878500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78935
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