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Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNA
The effects of lysine peptide lengths on DNA and siRNA packaging and delivery were studied using four linear oligolysine peptides with 8 (K8), 16 (K16), 24 (K24) and 32 (K32) lysines. Oligolysine peptides with 16 lysines or longer were effective for stable monodisperse particle formation and optimal...
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| Publicado no: | Chem Biol Drug Des |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4991294/ https://ncbi.nlm.nih.gov/pubmed/26684657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12709 |
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