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A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency

Nonviral gene and small interfering RNA (siRNA) delivery formulations are extensively used for biological and therapeutic research in cell culture experiments, but less so in in vivo and clinical research. Difficulties with formulating the nanoparticles for uniformity and stability at concentrations...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Tagalakis, Aristides D, Castellaro, Sara, Zhou, Haiyan, Bienemann, Alison, Munye, Mustafa M, McCarthy, David, White, Edward A, Hart, Stephen L
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388080/
https://ncbi.nlm.nih.gov/pubmed/25878500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78935
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