Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery

RNAi induced by double-stranded small interfering RNA (siRNA) molecules has attracted great attention as a naturally occurring approach to silence gene expression with high specificity. The myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway is a master regulator of cytos...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Fernando, Owen, Tagalakis, Aristides D., Awwad, Sahar, Brocchini, Steve, Khaw, Peng T., Hart, Stephen L., Yu-Wai-Man, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277485/
https://ncbi.nlm.nih.gov/pubmed/30301666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.09.004
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