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Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells

Cystic fibrosis (CF) is a lethal disease caused by mutations in the chloride channel CFTR gene. The disease is characterized by decreased chloride secretion and unregulated sodium absorption through the epithelial sodium channel (ENaC) in the airway epithelium and other affected organs. We hypothesi...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Henry, Katherine R., Lee, Seakwoo, Walker, Douglas, Zeitlin, Pamela L.
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley Periodicals, Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387756/
https://ncbi.nlm.nih.gov/pubmed/25626868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12264
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