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Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells

Cystic fibrosis (CF) is a lethal disease caused by mutations in the chloride channel CFTR gene. The disease is characterized by decreased chloride secretion and unregulated sodium absorption through the epithelial sodium channel (ENaC) in the airway epithelium and other affected organs. We hypothesi...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Henry, Katherine R., Lee, Seakwoo, Walker, Douglas, Zeitlin, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387756/
https://ncbi.nlm.nih.gov/pubmed/25626868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12264
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