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The Epithelial Sodium Channel (ENaC) as a Therapeutic Target for Cystic Fibrosis
Cystic fibrosis (CF) is a monogenic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR dysfunction is characterized by abnormal mucociliary transport due to a dehydrated airway surface liquid (ASL) and hyperviscous mucus, among other pathologies...
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| Publicado no: | Curr Opin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294660/ https://ncbi.nlm.nih.gov/pubmed/30340955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2018.09.007 |
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