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Inefficient clearance of myelin debris by microglia impairs remyelinating processes
An imbalance between remyelinating and demyelinating rates underlies degenerative processes in demyelinating diseases such as multiple sclerosis. An optimal therapeutic strategy would be to stimulate remyelination while limiting demyelination. Although accumulation of myelin debris impairs remyelina...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387282/ https://ncbi.nlm.nih.gov/pubmed/25779633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141656 |
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