Inefficient clearance of myelin debris by microglia impairs remyelinating processes

An imbalance between remyelinating and demyelinating rates underlies degenerative processes in demyelinating diseases such as multiple sclerosis. An optimal therapeutic strategy would be to stimulate remyelination while limiting demyelination. Although accumulation of myelin debris impairs remyelina...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Lampron, Antoine, Larochelle, Antoine, Laflamme, Nathalie, Préfontaine, Paul, Plante, Marie-Michèle, Sánchez, Maria Gabriela, Yong, V. Wee, Stys, Peter K., Tremblay, Marie-Ève, Rivest, Serge
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387282/
https://ncbi.nlm.nih.gov/pubmed/25779633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141656
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