IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity

INTRODUCTION: Multiple sclerosis (MS) is a chronic demyelinating disorder of the central nervous system (CNS) leading to progressive neurological disability. Interferon β (IFNβ) represents a standard treatment for relapsing-remitting MS and exogenous administration of IFNβ exhibits protective effect...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kocur, Magdalena, Schneider, Reiner, Pulm, Ann-Kathrin, Bauer, Jens, Kropp, Sonja, Gliem, Michael, Ingwersen, Jens, Goebels, Norbert, Alferink, Judith, Prozorovski, Timour, Aktas, Orhan, Scheu, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383054/
https://ncbi.nlm.nih.gov/pubmed/25853624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0192-4
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