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Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models

OBJECTIVE: There is increasing pre-clinical evidence indicating that metformin, a medication commonly used for type 2 diabetes, may protect against cancer. Motivated by this emerging evidence we asked two questions: (a) can metformin prevent ovarian cancer growth by altering metabolism, and (b) will...

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Detaylı Bibliyografya
Yayımlandı:Am J Obstet Gynecol
Asıl Yazarlar: LENGYEL, Ernst, LITCHFIELD, Lacey M., MITRA, Anirban K., NIEMAN, Kristin M., MUKHERJEE, Abir, ZHANG, Yilin, JOHNSON, Alyssa, BRADARIC, Michael, LEE, WooSeok, ROMERO, Iris L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387077/
https://ncbi.nlm.nih.gov/pubmed/25446664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2014.10.026
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