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Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus

Exposure to high levels of organophosphorus compounds (OP) can induce status epilepticus (SE) in humans and rodents via acute cholinergic toxicity, leading to neurodegeneration and brain inflammation. Currently there is no treatment to combat the neuropathologies associated with OP exposure. We rece...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Rojas, Asheebo, Ganesh, Thota, Lelutiu, Nadia, Gueorguieva, Paoula, Dingledine, Raymond
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387070/
https://ncbi.nlm.nih.gov/pubmed/25656476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.01.017
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