The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus

Prostaglandin E2 (PGE2) regulates membrane excitability, synaptic transmission, plasticity, and neuronal survival. The consequences of PGE2 release following seizures has been the subject of much study. Here we demonstrate that the prostaglandin E2 receptor 1 (EP1, or Ptger1) modulates native kainat...

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Hlavní autoři: Rojas, Asheebo, Gueorguieva, Paoula, Lelutiu, Nadia, Quan, Yi, Shaw, Renee, Dingledine, Raymond
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130787/
https://ncbi.nlm.nih.gov/pubmed/24952362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.004
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