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A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition

This review describes an adult rat model of status epilepticus (SE) induced by diisopropyl fluorophosphate (DFP), and the beneficial outcomes of transient inhibition of the prostaglandin-E(2) receptor EP2 with a small molecule antagonist, delayed by 2-4h after SE onset. Administration of six doses o...

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Dades bibliogràfiques
Publicat a:Neurobiol Dis
Autors principals: Rojas, Asheebo, Ganesh, Thota, Wang, Wenyi, Wang, Jennifer, Dingledine, Raymond
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708729/
https://ncbi.nlm.nih.gov/pubmed/30818067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.010
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