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A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition

This review describes an adult rat model of status epilepticus (SE) induced by diisopropyl fluorophosphate (DFP), and the beneficial outcomes of transient inhibition of the prostaglandin-E(2) receptor EP2 with a small molecule antagonist, delayed by 2-4h after SE onset. Administration of six doses o...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neurobiol Dis
Päätekijät: Rojas, Asheebo, Ganesh, Thota, Wang, Wenyi, Wang, Jennifer, Dingledine, Raymond
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708729/
https://ncbi.nlm.nih.gov/pubmed/30818067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.010
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