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A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition

This review describes an adult rat model of status epilepticus (SE) induced by diisopropyl fluorophosphate (DFP), and the beneficial outcomes of transient inhibition of the prostaglandin-E(2) receptor EP2 with a small molecule antagonist, delayed by 2-4h after SE onset. Administration of six doses o...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Rojas, Asheebo, Ganesh, Thota, Wang, Wenyi, Wang, Jennifer, Dingledine, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708729/
https://ncbi.nlm.nih.gov/pubmed/30818067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.010
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