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Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus

Exposure to high levels of organophosphorus compounds (OP) can induce status epilepticus (SE) in humans and rodents via acute cholinergic toxicity, leading to neurodegeneration and brain inflammation. Currently there is no treatment to combat the neuropathologies associated with OP exposure. We rece...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Rojas, Asheebo, Ganesh, Thota, Lelutiu, Nadia, Gueorguieva, Paoula, Dingledine, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387070/
https://ncbi.nlm.nih.gov/pubmed/25656476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.01.017
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