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Homology and enzymatic requirements of microhomology-dependent alternative end joining

Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of classical NHEJ and is implicated in chromosomal translocations leading to cancer. In the presen...

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Vydáno v:Cell Death Dis
Hlavní autoři: Sharma, S, Javadekar, S M, Pandey, M, Srivastava, M, Kumari, R, Raghavan, S C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385936/
https://ncbi.nlm.nih.gov/pubmed/25789972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.58
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