SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

Mounting evidence indicates that S-Phase Kinase-Associated Protein 2 (SKP2) is overexpressed in human hepatocellular carcinoma (HCC). However, the role of SKP2 in hepatocarcinogenesis remains poorly delineated. To elucidate the function(s) of SKP2 in HCC, we stably overexpressed the SKP2 gene in the...

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Publicado en:Oncotarget
Autores principales: Delogu, Salvatore, Wang, Chunmei, Cigliano, Antonio, Utpatel, Kirsten, Sini, Marcella, Longerich, Thomas, Waldburger, Nina, Breuhahn, Kai, Jiang, Lijie, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin, Calvisi, Diego F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385847/
https://ncbi.nlm.nih.gov/pubmed/25537506
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