SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

Mounting evidence indicates that S-Phase Kinase-Associated Protein 2 (SKP2) is overexpressed in human hepatocellular carcinoma (HCC). However, the role of SKP2 in hepatocarcinogenesis remains poorly delineated. To elucidate the function(s) of SKP2 in HCC, we stably overexpressed the SKP2 gene in the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Delogu, Salvatore, Wang, Chunmei, Cigliano, Antonio, Utpatel, Kirsten, Sini, Marcella, Longerich, Thomas, Waldburger, Nina, Breuhahn, Kai, Jiang, Lijie, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin, Calvisi, Diego F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385847/
https://ncbi.nlm.nih.gov/pubmed/25537506
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