Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Castration-Resistant Prostate Cancer Patients Treated with Abiraterone

PURPOSE: Gene fusions leading to androgen receptor–modulated ERG overexpression occur in up to 70% of metastatic castration-resistant prostate cancers (mCRPC). We assessed the association between ERG rearrangement status and clinical benefit from abiraterone. EXPERIMENTAL DESIGN: COU-AA-302 is a pha...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Attard, Gerhardt, de Bono, Johann S., Logothetis, Christopher J., Fizazi, Karim, Mukherjee, Som D., Joshua, Anthony M., Schrijvers, Dirk, van den Eertwegh, Alfons J.M., Li, Weimin, Molina, Arturo, Griffin, Thomas W., Kheoh, Thian, Ricci, Deborah S., Zelinsky, Kathy, Rathkopf, Dana E., Scher, Howard I., Ryan, Charles J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384987/
https://ncbi.nlm.nih.gov/pubmed/25593303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1961
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