Does Gleason score at initial diagnosis predict efficacy of abiraterone acetate therapy in patients with metastatic castration-resistant prostate cancer? An analysis of abiraterone acetate phase III trials

BACKGROUND: The usefulness of Gleason score (<8 or ≥8) at initial diagnosis as a predictive marker of response to abiraterone acetate (AA) plus prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) was explored retrospectively. PATIENTS AND METHODS: Initial diagnosis...

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Udgivet i:Ann Oncol
Main Authors: Fizazi, K., Flaig, T. W., Stöckle, M., Scher, H. I., de Bono, J. S., Rathkopf, D. E., Ryan, C. J., Kheoh, T., Li, J., Todd, M. B., Griffin, T. W., Molina, A., Ohlmann, C. H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279107/
https://ncbi.nlm.nih.gov/pubmed/26609008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv545
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