Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Castration-Resistant Prostate Cancer Patients Treated with Abiraterone

PURPOSE: Gene fusions leading to androgen receptor–modulated ERG overexpression occur in up to 70% of metastatic castration-resistant prostate cancers (mCRPC). We assessed the association between ERG rearrangement status and clinical benefit from abiraterone. EXPERIMENTAL DESIGN: COU-AA-302 is a pha...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Attard, Gerhardt, de Bono, Johann S., Logothetis, Christopher J., Fizazi, Karim, Mukherjee, Som D., Joshua, Anthony M., Schrijvers, Dirk, van den Eertwegh, Alfons J.M., Li, Weimin, Molina, Arturo, Griffin, Thomas W., Kheoh, Thian, Ricci, Deborah S., Zelinsky, Kathy, Rathkopf, Dana E., Scher, Howard I., Ryan, Charles J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384987/
https://ncbi.nlm.nih.gov/pubmed/25593303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1961
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