Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Castration-Resistant Prostate Cancer Patients Treated with Abiraterone

PURPOSE: Gene fusions leading to androgen receptor–modulated ERG overexpression occur in up to 70% of metastatic castration-resistant prostate cancers (mCRPC). We assessed the association between ERG rearrangement status and clinical benefit from abiraterone. EXPERIMENTAL DESIGN: COU-AA-302 is a pha...

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Publicado no:Clin Cancer Res
Main Authors: Attard, Gerhardt, de Bono, Johann S., Logothetis, Christopher J., Fizazi, Karim, Mukherjee, Som D., Joshua, Anthony M., Schrijvers, Dirk, van den Eertwegh, Alfons J.M., Li, Weimin, Molina, Arturo, Griffin, Thomas W., Kheoh, Thian, Ricci, Deborah S., Zelinsky, Kathy, Rathkopf, Dana E., Scher, Howard I., Ryan, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384987/
https://ncbi.nlm.nih.gov/pubmed/25593303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1961
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