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A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores

Kinetochore (KT) localization of mitotic checkpoint proteins is essential for their function during mitosis. hSpindly KT localization is dependent on the RZZ complex and hSpindly recruits the dynein–dynactin complex to KTs during mitosis, but the mechanism of hSpindly KT recruitment is unknown. Thro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Cell Biol
मुख्य लेखकों: Moudgil, Devinderjit K., Westcott, Nathan, Famulski, Jakub K., Patel, Kinjal, Macdonald, Dawn, Hang, Howard, Chan, Gordon K.T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384735/
https://ncbi.nlm.nih.gov/pubmed/25825516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412085
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