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A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores
Kinetochore (KT) localization of mitotic checkpoint proteins is essential for their function during mitosis. hSpindly KT localization is dependent on the RZZ complex and hSpindly recruits the dynein–dynactin complex to KTs during mitosis, but the mechanism of hSpindly KT recruitment is unknown. Thro...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384735/ https://ncbi.nlm.nih.gov/pubmed/25825516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412085 |
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