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Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint

The mitotic checkpoint is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. Mitotic checkpoint function depends on numerous kinetochore proteins, including ZW10, ROD, and Zwilch (the ROD–ZW10–Zwilch complex). Through an extensive mutagenesis screen...

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Bibliografische gegevens
Hoofdauteurs: Famulski, Jakub K., Vos, Larissa, Sun, Xuejun, Chan, Gordon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234252/
https://ncbi.nlm.nih.gov/pubmed/18268100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708021
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