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Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint

The mitotic checkpoint is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. Mitotic checkpoint function depends on numerous kinetochore proteins, including ZW10, ROD, and Zwilch (the ROD–ZW10–Zwilch complex). Through an extensive mutagenesis screen...

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Detalhes bibliográficos
Main Authors: Famulski, Jakub K., Vos, Larissa, Sun, Xuejun, Chan, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234252/
https://ncbi.nlm.nih.gov/pubmed/18268100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708021
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