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Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint

The mitotic checkpoint is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. Mitotic checkpoint function depends on numerous kinetochore proteins, including ZW10, ROD, and Zwilch (the ROD–ZW10–Zwilch complex). Through an extensive mutagenesis screen...

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Hlavní autoři: Famulski, Jakub K., Vos, Larissa, Sun, Xuejun, Chan, Gordon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234252/
https://ncbi.nlm.nih.gov/pubmed/18268100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708021
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