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A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores

Kinetochore (KT) localization of mitotic checkpoint proteins is essential for their function during mitosis. hSpindly KT localization is dependent on the RZZ complex and hSpindly recruits the dynein–dynactin complex to KTs during mitosis, but the mechanism of hSpindly KT recruitment is unknown. Thro...

詳細記述

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書誌詳細
出版年:J Cell Biol
主要な著者: Moudgil, Devinderjit K., Westcott, Nathan, Famulski, Jakub K., Patel, Kinjal, Macdonald, Dawn, Hang, Howard, Chan, Gordon K.T.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384735/
https://ncbi.nlm.nih.gov/pubmed/25825516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412085
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