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Reactivation of latent HIV-1 by new semi-synthetic ingenol esters
The ability of HIV to establish long-lived latent infection is mainly due to transcriptional silencing of viral genome in resting memory T lymphocytes. Here, we show that new semi-synthetic ingenol esters reactivate latent HIV reservoirs. Amongst the tested compounds, 3-caproyl-ingenol (ING B) was m...
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| Publicado no: | Virology |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383768/ https://ncbi.nlm.nih.gov/pubmed/25014309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.05.033 |
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