Reactivation of latent HIV-1 by new semi-synthetic ingenol esters

The ability of HIV to establish long-lived latent infection is mainly due to transcriptional silencing of viral genome in resting memory T lymphocytes. Here, we show that new semi-synthetic ingenol esters reactivate latent HIV reservoirs. Amongst the tested compounds, 3-caproyl-ingenol (ING B) was m...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Virology
Main Authors: José, Diego Pandeló, Bartholomeeusen, Koen, da Cunha, Rodrigo Delvecchio, Abreu, Celina Monteiro, Glinski, Jan, da Costa, Thais Barbizan Ferreira, Rabay, Ana Flávia Mello Bacchi, Filho, Luiz Francisco Pianowski, Dudycz, Lech W., Ranga, Udaykumar, Peterlin, Boris Matija, Pianowski, Luiz Francisco, Tanuri, Amilcar, Aguiar, Renato Santana
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383768/
https://ncbi.nlm.nih.gov/pubmed/25014309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.05.033
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker