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Histone Deacetylase Inhibitors (HDACis) That Release the Positive Transcription Elongation Factor b (P-TEFb) from Its Inhibitory Complex Also Activate HIV Transcription

Numerous studies have looked at the effects of histone deacetylase inhibitors (HDACis) on HIV reactivation in established transformed cell lines and primary CD4(+) T cells. However, their findings remain confusing, and differences between effects of class I- and class II-specific HDACis persist. Bec...

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Detalhes bibliográficos
Main Authors: Bartholomeeusen, Koen, Fujinaga, Koh, Xiang, Yanhui, Peterlin, B. Matija
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656295/
https://ncbi.nlm.nih.gov/pubmed/23539624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464834
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