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Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein (snRNP) Activates Hexamethylene Bisacetamide-inducible Protein (HEXIM1) Transcription

By phosphorylating negative elongation factors and the C-terminal domain of RNA polymerase II (RNAPII), positive transcription elongation factor b (P-TEFb), which is composed of CycT1 or CycT2 and CDK9, activates eukaryotic transcription elongation. In growing cells, it is found in active and inacti...

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書誌詳細
主要な著者: Liu, Pingyang, Xiang, Yanhui, Fujinaga, Koh, Bartholomeeusen, Koen, Nilson, Kyle A., Price, David H., Peterlin, B. Matija
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975036/
https://ncbi.nlm.nih.gov/pubmed/24515107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539015
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