Pharmacological Inhibition of FTO

In 2007, a genome wide association study identified a SNP in intron one of the gene encoding human FTO that was associated with increased body mass index. Homozygous risk allele carriers are on average three kg heavier than those homozygous for the protective allele. FTO is a DNA/RNA demethylase, ho...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: McMurray, Fiona, Demetriades, Marina, Aik, WeiShen, Merkestein, Myrte, Kramer, Holger, Andrew, Daniel S., Scudamore, Cheryl L., Hough, Tertius A., Wells, Sara, Ashcroft, Frances M., McDonough, Michael A., Schofield, Christopher J., Cox, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382163/
https://ncbi.nlm.nih.gov/pubmed/25830347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121829
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