FTO influences adipogenesis by regulating mitotic clonal expansion

The fat mass and obesity-associated (FTO) gene plays a pivotal role in regulating body weight and fat mass; however, the underlying mechanisms are poorly understood. Here we show that primary adipocytes and mouse embryonic fibroblasts (MEFs) derived from FTO overexpression (FTO-4) mice exhibit incre...

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Publicat a:Nat Commun
Autors principals: Merkestein, Myrte, Laber, Samantha, McMurray, Fiona, Andrew, Daniel, Sachse, Gregor, Sanderson, Jeremy, Li, Mengdi, Usher, Samuel, Sellayah, Dyan, Ashcroft, Frances M., Cox, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410642/
https://ncbi.nlm.nih.gov/pubmed/25881961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7792
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