Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

Lignende værker

• Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
  af: Gao, Pu, et al.
  Udgivet: (2013)
• Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
  af: Gao, Pu, et al.
  Udgivet: (2013)
• INSECT STING OF THE LID—AND A SEQUEL
  af: Law, Frank W.
  Udgivet: (1958)
• Mouse, but not human STING, binds and signals in response to the vascular disrupting agent DMXAA
  af: Conlon, Joseph, et al.
  Udgivet: (2013)
• G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes
  af: Herzner, Anna-Maria, et al.
  Udgivet: (2016)