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G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes

Excessive inflammation can cause damage to host cells and tissues. Thus, the secretion of inflammatory cytokines is tightly regulated at transcriptional, post-transcriptional and post-translational levels and influenced by cellular stress responses, such as endoplasmic reticulum (ER) stress or apopt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Herzner, Anna-Maria, Wolter, Steven, Zillinger, Thomas, Schmitz, Saskia, Barchet, Winfried, Hartmann, Gunther, Bartok, Eva, Schlee, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150577/
https://ncbi.nlm.nih.gov/pubmed/27941826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38405
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