Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

During blood-stage malaria, the innate immune system initiates the production of pro-inflammatory cytokines, including IFN-γ, that are critical to host defense and responsible for severe disease. Nonetheless, the innate immune pathways activated during this process in human malaria remain poorly und...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Coch, Christoph, Hommertgen, Benjamin, Zillinger, Thomas, Daßler-Plenker, Juliane, Putschli, Bastian, Nastaly, Maximilian, Kümmerer, Beate M., Scheunemann, Johanna F., Schumak, Beatrix, Specht, Sabine, Schlee, Martin, Barchet, Winfried, Hoerauf, Achim, Bartok, Eva, Hartmann, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445952/
https://ncbi.nlm.nih.gov/pubmed/30972055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00371
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