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Effect of minichromosome maintenance protein 2 deficiency on the locations of DNA replication origins
Minichromosome maintenance (MCM) proteins are loaded onto chromatin during G1-phase and define potential locations of DNA replication initiation. MCM protein deficiency results in genome instability and high rates of cancer in mouse models. Here we develop a method of nascent strand capture and rele...
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| Gepubliceerd in: | Genome Res |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381527/ https://ncbi.nlm.nih.gov/pubmed/25762552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.176099.114 |
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