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A Signature of Genomic Instability Resulting from Deficient Replication Licensing

Insufficient licensing of DNA replication origins has been shown to result in genome instability, stem cell deficiency, and cancers. However, it is unclear whether the DNA damage resulting from deficient replication licensing occurs generally or if specific sites are preferentially affected. To map...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Pruitt, Steven C., Qin, Maochun, Wang, Jianmin, Kunnev, Dimiter, Freeland, Amy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242545/
https://ncbi.nlm.nih.gov/pubmed/28045896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006547
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