Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

In addition to mediating sister chromatid cohesion during the cell cycle, the cohesin complex associates with CTCF and with active gene regulatory elements to form long-range interactions between its binding sites. Genome-wide chromosome conformation capture had shown that cohesin's main role i...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Ing-Simmons, Elizabeth, Seitan, Vlad C., Faure, Andre J., Flicek, Paul, Carroll, Thomas, Dekker, Job, Fisher, Amanda G., Lenhard, Boris, Merkenschlager, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381522/
https://ncbi.nlm.nih.gov/pubmed/25677180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.184986.114
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