Initiation and maintenance of pluripotency gene expression in the absence of cohesin

Cohesin is implicated in establishing and maintaining pluripotency. Whether this is because of essential cohesin functions in the cell cycle or in gene regulation is unknown. Here we tested cohesin’s contribution to reprogramming in systems that reactivate the expression of pluripotency genes in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Lavagnolli, Thais, Gupta, Preksha, Hörmanseder, Eva, Mira-Bontenbal, Hegias, Dharmalingam, Gopuraja, Carroll, Thomas, Gurdon, John B., Fisher, Amanda G., Merkenschlager, Matthias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281562/
https://ncbi.nlm.nih.gov/pubmed/25561493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251835.114
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