Initiation and maintenance of pluripotency gene expression in the absence of cohesin

Cohesin is implicated in establishing and maintaining pluripotency. Whether this is because of essential cohesin functions in the cell cycle or in gene regulation is unknown. Here we tested cohesin’s contribution to reprogramming in systems that reactivate the expression of pluripotency genes in the...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Lavagnolli, Thais, Gupta, Preksha, Hörmanseder, Eva, Mira-Bontenbal, Hegias, Dharmalingam, Gopuraja, Carroll, Thomas, Gurdon, John B., Fisher, Amanda G., Merkenschlager, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281562/
https://ncbi.nlm.nih.gov/pubmed/25561493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.251835.114
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