Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

Chromosome conformation capture approaches have shown that interphase chromatin is partitioned into spatially segregated Mb-sized compartments and sub-Mb-sized topological domains. This compartmentalization is thought to facilitate the matching of genes and regulatory elements, but its precise funct...

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Detalhes bibliográficos
Main Authors: Seitan, Vlad C., Faure, Andre J., Zhan, Ye, McCord, Rachel Patton, Lajoie, Bryan R., Ing-Simmons, Elizabeth, Lenhard, Boris, Giorgetti, Luca, Heard, Edith, Fisher, Amanda G., Flicek, Paul, Dekker, Job, Merkenschlager, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847776/
https://ncbi.nlm.nih.gov/pubmed/24002784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161620.113
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