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Transcription of RORγt in Developing Th17 Cells is Regulated by E-Proteins

In the present study we investigated the molecular mechanisms regulating the expression of RORγt, the central factor controlling IL-17 transcription and Th17 differentiation. In key studies we found that cells from mice with major deletions of the E-protein transcription factors, E2A and HEB, displa...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Zhang, Fuping, Fuss, Ivan J., Yang, Zhiqiong, Strober, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381430/
https://ncbi.nlm.nih.gov/pubmed/24064669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.69
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