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The Th17-Defining Transcription Factor RORγt Promotes Glomerulonephritis
Although Th17 responses may contribute to the pathogenesis of glomerulonephritis, whether the key transcription factor in Th17 cell development, RORγt, also promotes glomerulonephritis is unknown. Here, we induced crescentic glomerulonephritis in wild-type and RORγt-deficient (RORγt(−/−)) mice. RORγ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060441/ https://ncbi.nlm.nih.gov/pubmed/21183590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040435 |
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