Signal transducer and activation of transcription 6 (STAT6) regulates T helper type 1 (Th1) and Th17 nephritogenic immunity in experimental crescentic glomerulonephritis

Experimental crescentic glomerulonephritis is driven by systemic cellular immune responses. A pathogenic role for T helper type 1 (Th1) and Th17 cells is well established. T-bet, a key transcription factor required for Th1 lineage commitment, and retinoic acid-related orphan receptor-γt (Rorγt), a k...

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Hlavní autoři: Summers, S A, Phoon, R K S, Odobasic, D, Dewage, L, Kitching, A R, Holdsworth, S R
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Translational Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219898/
https://ncbi.nlm.nih.gov/pubmed/21985369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04437.x
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