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The IL-27 Receptor Has Biphasic Effects in Crescentic Glomerulonephritis Mediated Through Th1 Responses

Despite its initially defined role as a T-helper type 1 cell (Th1)–inducing cytokine, interleukin-27 (IL-27) has complex roles in vivo. The role of IL-27 receptor (IL-27R) was defined in experimental crescentic glomerulonephritis induced by a foreign antigen, sheep globulin, which is planted in glom...

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Détails bibliographiques
Auteurs principaux: Summers, Shaun A., Phoon, Richard K.S., Ooi, Joshua D., Holdsworth, Stephen R., Kitching, A. Richard
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069896/
https://ncbi.nlm.nih.gov/pubmed/21281790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.013
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